Procedure Guide
Rejuran Skin Booster Guide : Benefits, Types, and Ideal Candidates
Oct 13, 2026
Rejuran is a renowned South Korean skin rejuvenation procedure that has taken the aesthetic world by storm. Known for its ability to restore elasticity, boost radiance, and combat early signs of aging, this popular injectable utilizes Polynucleotides (PN) derived from salmon DNA to repair damaged skin cells from within.
In this guide, we’ll break down the different types of Rejuran, their key benefits, and how to know if this viral "skin booster" is right for your skincare goals.
<Table of Content>
1. What Is Rejuran?
2. Types of Rejuran
3. Effects of Rejuran
4. Ideal Candidates for Rejuran
5. Final Thoughts

1. What Is Rejuran?
Rejuran is an injectable skin procedure formulated with Polynucleotides (PN) extracted from salmon DNA. Injected directly into the dermis, it enhances the skin's natural repair mechanisms and regenerates damaged cells.
Often referred to as the "Salmon DNA Injection," its core component, Polynucleotide, promotes skin cell regeneration and repair, boosting the skin's self-healing capacity. As a result, this procedure helps restore elasticity, improve skin firmness, and reduce the appearance of fine lines.

2. Types of Rejuran
Rejuran comes in four distinct formulas designed to target specific skin concerns and areas, allowing for a tailored approach to procedure. Whether you are addressing fine lines, acne scarring, or dry skin, regular sessions promote fundamental, long-term skin regeneration.
Rejuran Healer (Standard)
This is the classic, foundational Rejuran formula suitable for full-face rejuvenation and general skin repairs.
👀 Target Areas
→ Full face, neck, décolletage, and hands.
Rejuran i (Specialized for Eyes)
The "i" in Rejuran i stands for "Eye," as this formula is specifically tailored for the delicate eye area. It features a lower viscosity and finer particle size than Rejuran Healer, ensuring smoother integration with minimal pain and swelling in thin skin.
👀 Target Areas
→ Under-eye region (dark circles, fine lines) and crow's feet.
Rejuran S (Specialized for Scar Repair)
The "S" in Rejuran S stands for "Scar." It features the highest viscosity among the Rejuran line, making it ideal for targeted procedure of depressed areas such as acne scars and pitted skin.
👀 Target Areas
→ Acne scars and localized indentations on the cheeks, temples, chin, or other affected zones.
Rejuran HB (Formulated with Hyaluronic Acid)
Rejuran HB combines the core Polynucleotide (PN) formula of Rejuran Healer with Hyaluronic Acid (HA), delivering simultaneous cellular regeneration and intense hydration.
👀 Target Areas
→ Dry or dehydrated areas such as the cheeks, forehead, and neck.

3. Benefits of Rejuran
The key to Rejuran's effectiveness lies in boosting the skin's natural self-healing ability. Unlike hyaluronic acid fillers or Botox, which alter facial structure or shape, Rejuran activates skin cells from within to fundamentally repair and regenerate the tissue itself.
Promotes Skin Regeneration
The primary ingredient, salmon-derived polynucleotide, activates dermal fibroblasts. These fibroblasts not only synthesize collagen and elastin to rebuild and strengthen skin structure, but also soothe inflammation to repair skin damaged by UV rays and other stressors.
Smooth Fine Lines & Restore Elasticity
By boosting collagen production, it increases skin thickness and elasticity, paving the way for a plump, youthful complexion free from fine lines and sagging.
Soothe Redness, Inflammation & Sensitivity
It repairs the skin barrier, strengthening skin against external irritants. By reducing inflammation, it is also effective for facial redness, rough skin, and sensitivity.
Improve Under-Eye Dark Circles
Promoting the creation and regeneration of capillaries is key to improving under-eye dark circles. By restoring firmness and elasticity, Rejuran improves dark circles caused by skin sagging, while also encouraging melanin turnover to effectively fade hyperpigmentation.
Why Rejuran Results Might Feel Hard to Notice
In general, most skin regeneration procedures require multiple sessions to achieve their intended results, and Rejuran is no exception—a single session may make it difficult to notice significant changes. Furthermore, because this procedure works gradually as the skin transforms over time rather than offering immediate results, it may not be suitable for those seeking instant or short-term fixes.
Additionally, if the injection fails to reach the intended depth, location, or dosage, you may not achieve the expected results. Choosing a clinic with highly skilled practitioners who can precisely administer injections to target areas is crucial.

4. Ideal Candidates for Rejuran
Those experiencing loss of skin firmness with age
→ As we reach our 30s and beyond, natural collagen and elastin production decreases sharply. Rejuran stimulates the skin's self-regeneration process, helping to restore firmness and elasticity from within.
Those concerned about fine lines and crepey skin
→ Rejuran simultaneously boosts hydration and cellular repair, making it particularly effective for fine lines caused by dryness. It can also be safely administered around high-movement areas such as the eyes and mouth.
Those with a weakened skin barrier
→ Sensitive or easily damaged skin often lacks natural recovery power. Rejuran promotes deep repair within the dermal layer to strengthen the barrier function, building resilient skin that resists future irritation.
Those concerned about acne scars and enlarged pores
→ Rejuran works by repairing damaged skin cells and regulating cell turnover, helping to improve post-inflammatory hyperpigmentation and pitted acne scars.
For those seeking natural anti-aging care
→ Unlike Botox or dermal fillers, which alter facial structure or expression, Rejuran utilizes your skin's natural recovery power. It is perfect for anyone seeking a subtle, natural-looking result without looking artificial or overdone.
Rejuran comes in four distinct types tailored to individual skin concerns. Receiving regular sessions with the formula best suited to your needs allows you to experience the full, intended benefits of the procedure.

Final Thoughts
Rejuran is an ideal procedure for anyone looking to regenerate their skin from within and restore a natural, healthy glow.
While the results develop gradually, consistent procedures unlock your skin’s full potential over time. To ensure a personalized procedure plan tailored to your specific needs, we recommend consulting with an experienced aesthetic practitioner or trusted clinic.
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